2014年4月9日星期三

Orexin A (human, rat, mouse)

Orexin A (human, rat, mouse)

Cat. No. 1455

Orexin A (human, rat, mouse) pGlu-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 (Disulfide bridge: 6-12 and 7-14)


Biological Activity

Endogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions.

Technical Data

M.Wt:
3561.12
Formula:
C152H243N47O44S4
Sequence:
XPLPDCCRQKTCSCRLYELLHGAGNHAAGILTL
(Modifications: X = pGlu, Disulfide bridge between 6 - 12, 7 - 14, Leu-33 = C-terminal amide)
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
205640-90-0
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

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